Browsing by Author "Gunawardhana, S.M."

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Behaviour patterns of chronic kidney patients in North Central province of Sri Lanka
(Sri Lanka Association for the Advancement of Science, 2008) Gunawardhana, S.M.; Liyanage, J.A.
North Central Province (NCP) is a major part of the dry zone of Sri Lanka. An increasing trend in admission of patients with renal diseases to hospitals is shown in Anuradhapura, Polonnaruwa, Monaragala and Badulla administrative districts. In NCP itself, over 5,000 patients are on treatment for Chronic Kidney Diseases (CKD) with unknown etiology. Hence a survey was conducted to collect information related to socio-economic factors and behaviour patterns of the patients who attending the renal clinics in Anuradhapura and Madawachchiya hospitals. The total number of patients questioned was 240 and they were found to be suffering from early stage of the disease. According to the results 89% of the patients who participated in the survey are farmers and their helpers. The age group of patients is the other most significant finding. That is 61% of the total patients are in the age between 30 and 60 years. This shows that unidentified factors related to CKD are not suddenly affected the individuals. They are functioning or accumulating in the human body for a long period of time. The survey showed that exposure to agrochemicals including chemical fertilizers, insecticides, herbicides and fungicides is common for 55% of the CKD patients. Of the patients 69% do not consume alcohol but most of them have stopped consuming alcohol after the CKD symptoms appeared. It also showed that the prevalence of the disease is more common in males (69%) than in females and 93%t of the patients use groundwater for the drinking and household purposes.
Quality of water consumed by chronic kidney patients in North Central province of Sri Lanka
(Sri Lanka Association for the Advancement of Science, 2008) Gunawardhana, S.M.; Liyanage, J.A.
The population of the North Central Province (NCP) is about 1.2 million and geographically it is the largest province in the country. Majority of rural population living in the area are farmers and they largely depend on the ground and surface water sources for their day to day life. At present, over 5,000 patients in NCP are on treatment for Chronic Kidney Diseases (CKD) and the etiology for this disease still remains a mystery. ‘Heavy metals’ are chemical elements with a specific gravity that is at least 5 times the specific gravity of water. Living organisms require trace amounts of some essential metals but excessive levels can be detrimental to the organisms. Toxic metals have no known vital or beneficial effect on organisms, and their accumulation over a period of time in human bodies can cause serious illnesses like CKD. In addition, some potential triggering factors for CKD are PO43-, SO42-, F- and Mg. According to the surveys done in Anuradhapura and Madawachchiya renal clinics, two affected areas Wewalkatiya and Nikiniyawa villages in Anuradhapura district and a reference village, Kohalwila, where no CKD patients were found were selected for water quality testing. The water distribution reservoir in Kekirawa affected area, Malawa tank, was selected as the surface water source. Sampling was done from ground water wells in patient houses, Malawa tank and reference village in dry and wet seasons by collecting 3 samples at a point totally 20 points from a site. The concentrations of Fe, Al, Zn, Cu, Cd, Cr, Ca, Mg, Ni, Mn and Pb were determined by Atomic Absorption Spectrophotometry (AAS). The concentrations of total phosphorous, available phosphate, available sulphate and fluoride were determined by standard methods, pH was measured and total soluble ions were determined by conductivity measurements. The mean concentration of the analyzed metals in water samples from Anuradhapura district show very higher values than the reference site. Dissolved metal concentrations in analyzed water samples in affected areas do not exceed the Maximum Contaminated Levels set by the WHO for drinking water except for Al, Mn and Ni. The triggering factors of CKD, Mg, P, SO42-, PO43- and F- accumulated in water in the affected area are very high compared to the reference site. Although these concentrations reduce in wet season, these values are always higher than the values obtained for the reference site.