Browsing by Author "Karunaratne, T.D.N."

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A critical review of Mānasa roga (Mental Disease) in the Ayurveda Sanskrit texts
(Department of Sanskrit, University of Kelaniya, Kelaniya, 2016) Karunaratne, T.D.N.; Sugataratana Thero, Kahapola; Ariyawansa, H.A.S.; de Silva, H.A.
According to the data, there is a high prevalence of Mental Disease among elders of Sri Lanka. Prevalence of Dementia (Smruthibramsha) is 3% of elders in between the age of 60 to 80 years. This will be a big issue for Health policy planning and Health management. This study will be carried out to review classifications of mānasa roga, causative factors, signs and symptoms, treatment modalities of them in Sanskrit Authentic Ayurvedic texts viz Charaka Samhitha, Sussrutha Samhitha, vagbata Samhitha, Madawa Nidana, Bhavaprakasha, Bhela Samhitha and Ahstanga Samgraha. It is revealed that there is no definite pattern of classification of mānasa roga in Ayurvedic Sanskrit texts. Description of Mānasa roga are found in scatted form at different places in Sanskrit texts of Ayurveda. Mānasa roga can be mainly divided in to two types viz Unmāda and Apasmāra according to Ayurvedic Sanskrit authentic texts. Achārya Caraka has mentioned Unmāda, Apasmāra and Atathvābhinive^aya in two chapters in Cikithsā Sthāna of Caraka Samhitā as dominent mental illnesses. [1] Suśruta has mentioned Unmāda, Apasmāra and Amaānusopasarga in separate chapters in Uttara Tantra of Suśruta Samhitā. [2] Bhela Samhitā, Aṣṭānga Hṛdaya Samhitā, Aṣṭānga Sangraha and Mādhava Nidāna, Bhava Prakāṣa also followed the same pattern. [3]It is found that there are treatment modalities and managements of Manasa roga are different in text to text.
Standardization of sarasvatha choorna: used as a remedy for Dementia
(Science publishing Group, 2015) Karunaratne, T.D.N.; Sugataratana, K.; Ariyawansa, H.A.S.; de Silva, H.A.; Samarasingha, K.; Arawwawala, L.D.A.M.
Sri Lanka has been recognized as one of the fastest aging populations from the developing countries. There is a large senior population in the country. Since age is the biggest risk factor for Dementia, the need to create awareness and management is an increasing necessity. Sarasvatha Choorna is one of the polyherbal preparation used in Ayurveda for the management of Dementia which consists of 12 medicinal plants. In the present study, an attempt was made to standardize Sarasvatha Choorna by using standard protocols. Standardization was carried out by determination of total ash, water soluble ash, acid insoluble ash, microbial counts, heavy metals, phytochemical screening and development of TLC-densitogram fingerprints. Results revealed that 10.6±0.0% of total ash, 8.4±0.0% of water soluble ash 0.65±0.01% of acid insoluble ash 11.0±0.1% of cold ethanol extractable matter, 13.9±0.1% hot ethanol extractable matter, 13.9±0.1% cold water extractable matter and 20.2±0.2% hot water extractable matter were present in the Sarasvatha Choorna. Pathogenic microorganisms such as Coliforms, Escherichia coli and Salmonella were not found and heavy metal concentrations of Sarasvatha Choorna were well below the recommended upper limits for the tested heavy metals. Phytochemical screening studies revealed the presence of flavonoids, steroid glycosides and coumarins in both water and ethanol extracts of Sarasvatha Choorna. Presence of the raw materials in the Sarasvatha Choorna was confirmed by TLC fingerprints. Present study reveals the quality of Sarasvatha Choorna for the first time and quality control parameters resulted from this study can be used as a reference standard for quality control of Sarasvatha Choorna.