Browsing by Author "Kurukulasuriya, S.A.F."

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Comparing two different presentations of Takayasu arteritis
(Sri Lanka College of Internal Medicine, 2024) Kurukulasuriya, S.A.F.; Munidasa, D.
Reported here are two Asian patients with Takayasu arteritis (TA) with contrasting presentations and responses to treatment. The first patient was a 53-year-old man who presented with disabling abdominal pain. Imaging revealed thickening of the coeliac axis extending to common hepatic and splenic arteries causing external compression with luminal narrowing. There was uniform thickening of the aortic arch and the wall of the descending aorta along with retroperitoneal fibrosis. Early treatment resulted in almost complete remission in eight weeks. The second patient was a 48-year-old woman with pain down the left upper limb with eventual ischaemia of the fourth finger. Imaging revealed circumferential wall thickening at the origin of the left subclavian artery. Treatment started after 3 weeks of the initial presentation, and took up to 14 months for clinical improvement. The relative rarity of this disease and the heterogeneous nature of its clinical manifestations predispose to late diagnosis and delayed treatment. Clinical suspicion and relevant imaging are crucial for the early and accurate diagnosis and management of patients with TA.
Frozen shoulder following cardiac surgery; Sri Lankan experience
(Sri Lanka Medical Association, 2023) Kurukulasuriya, S.A.F.; Mettananda, K.C.D.; Jayaratne, K.I.W.G.M.N.
INTRODUCTION: A high incidence of frozen shoulder (FS), of up to 33% is reported in patients undergoing cardiac surgery, which is tenfold higher than in the normal population. Early diagnosis and treatment may prevent progression to chronic, treatment-resistant disease. OBJECTIVES: To study the incidence and associations of acute FS among a cohort of Sri Lankans undergoing coronary artery bypass graft, valve replacement or both cardiac surgeries. METHODS: An observational study was conducted in selected private-sector hospitals in Colombo. Sample size computed was 142 (110 males, mean age 60.28 yrs.) and convenience sampling technique was used where consecutive eligible patients were selected until the required sample size was S149 fulfilled. Patients were recruited to the study while in hospital and reviewed at the two-week and three-month routine follow-up visits. Interviewer administered questionnaire was used to document the demographic data and risk factor associations. Patients presenting with pain and restricted movement of the shoulder joint with positive limitation in lateral rotation, abduction, and medial rotation (LAM test) were considered as having frozen shoulders. RESULTS: Of the142 patients 40.1%(n=57) developed shoulder pain 38.7%(n=55) were LAM test positive. 38.7% (n=55) with both LAM test positivity and shoulder pain were confirmed as having FS. The highest number of patients developing FS were from the 50-60year age group (n=25). Of the associations, dyslipidaemia and ischemic heart disease had significant correlation with the diagnosis of FS (p value<0.05). CONCLUSIONS: More than one third of patients undergoing cardiac surgery developed FS. Ishaemic heat disease and dyslipidaemia showed significant correlation.
Incidence and prevalence of stroke and time trends in vascular risk factors among urban/semi-urban Sri Lankans: A population-based cohort study
(Ceylon College of Physicians, 2020) Mettananda, K.C.D.; Ranawaka, U.K.; Wickramarathna, K.B.; Kottahachchi, D.C.; Kurukulasuriya, S.A.F.; Matha, M.B.C.; Dassanayake, A.S.; Kasturiratne, K.T.A.A.; Pathmeswaran, A.; Wickremasinghe, A.R.; de Silva, H.J.
INTRODUCTION AND OBJECTIVES: Incidence of stroke is declining in developed countries, but is increasing in developing countries. There is no data on incidence of stroke in Sri Lanka, and only limited data on prevalence of stroke. METHODS: We studied a population-based cohort (35-64 years) selected by stratified random sampling from an urban/semi-urban health administrative area (Ragama Health Study) in 2007, and evaluated them again in 2014 with regard to new onset stroke and prevalence of vascular risk factors. Possible stroke patients were independently reviewed by a neurologist and a physician with regard to the diagnosis of stroke. The prevalence of stroke (at baseline) was estimated. Prevalence of vascular risk factors in the population were compared between 2007 and 2014. RESULTS: The baseline cohort in 2007 consisted of 2985 individuals (females 54.5%, mean age 52.4 ± 7.8 years). Of them, 2204 attended follow-up in 2014 (female 57.6%, mean age 59.2±7.6 years). 19 had a history of strokes at enrolment (stroke prevalence 6.37/1000 population) and 24 episodes of strokes occurred over the 7 years (annual incidence of stroke 1.56/1000 population). Risk factor prevalence in 2007 and 2014 were; hypertension 48.7% and 64.3%; hyperlipidaemia 35.5% and 39.3%; diabetes mellitus 28.2% and 35.7%; and obesity 2.6% and 17.9%, respectively. CONCLUSION: Stroke incidence and prevalence rates of Sri Lanka lie between those of developed and developing countries. Prevalence of vascular risks have increased over time in this urban/semi urban Sri Lankan population.
Knowledge on common snakes of Sri Lanka, bite prevention, first aid and associated factors among the adults of Ragama medical officer of health area
(Sri Lanka Medical Association, 2023) Jayasinghe, A.G.; Hettiarachchi, I.U.; Ilukpitiya, I.S.L.; Imanji, R.P.C.; Huzair, M.M.M.; Jayatissa, R.N.U.; Kurukulasuriya, S.A.F.
INTRODUCTION: Snakes, being keystone species in maintaining the existence of ecosystems, always have had a unique influence on humans throughout history. Poor public understanding of snakes has contributed to an increase in disease burden from snakebites. World Health Organisation identifies snake bites as a neglected tropical disease. OBJECTIVES: To evaluate the knowledge on common snakes of Sri Lanka and snakebites among the adults of Ragama Medical Officer of Health area. METHODS: A descriptive cross-sectional study was done using cluster sampling with a sample population of 637 residents (323 females, 314 males, mean age of the population 41.31, SD of 15.59). Interviewer administered questionnaire was used. A unified score was calculated for each participant considering ability to identify of common snakes, knowledge on venom status, bite prevention measures and first aid for snake bites. Participants who achieved 50% or above were attributed with 'good knowledge'. SPSS (version 22) was used. Statistically significant associations were identified by performing the Chi-square test. RESULTS: 59% of the total population had a 'good knowledge'. Of the highly venomous snakes, 98% identified Naja naja, 57% identified Daboia russelii, 44% identified Hypnale Spp and Craspedocephalus sp, 36% identified Bungaurus ceylonicus and 28% identified Bungarus caeruleus. Statistically significant associations regarding knowledge were recognised with sex, previous education on snakes and occupation. CONCLUSIONS: The population had a satisfactory knowledge and awareness on the domains examined. Statistically significant associations were noted between knowledge and sex, participants' occupation and previous education on snakes.
Prevalence of acute frozen shoulder with functional limitation following cardiac surgery: A descriptive study from Sri Lanka
(Ceylon College of Physicians, 2023) Kurukulasuriya, S.A.F.; Mettananda, K.C.D.
INTRODUCTION: A high incidence of frozen shoulder (FS), of up to 33% is reported in patients undergoing cardiac surgery, which is tenfold higher than in the normal population. Early diagnosis and treatment may prevent progression to chronic, treatmentresistant disease. However, data on the prevalence of acute FS following cardiac surgery in Sri Lanka is not known. The aim of this study was to identify the prevalence and associations of acute FS following coronary artery bypass graft with or without valve replacement in two cardiac surgical units in Sri Lanka. METHODS: We studied consecutive patients who underwent cardiac surgery from April 2022 to November 2022. Patients were recruited to the study before discharge from the hospital and were reviewed at 2 and 12 weeks following surgery. Acute FS was diagnosed in the presence of pain and limitation in lateral rotation, abduction, and medial rotation. Data on demographics and risk factors were collected using an interviewer-administered questionnaire. RESULTS: We studied 142 patients, 110 (77%) males, mean age of 60.3 SD years (range 28-78 years), 142 had coronary artery bypass grafting (CABG) and 3 of them additionally had valve replacement. Of them, 55 (38.7%) developed FS at 12 weeks post-surgery. Prevalence of FS was highest among the 50-60-year age group, 25 (45%). Development of post-surgical acute FS was more in patients with ischaemic heart disease (OR 5.5, p <0.01), hyperlipidaemia (OR 15.1, p<0.01), and who did not have regular post-op physiotherapy (6.1 p<0.01). CONCLUSION: More than one-third of patients undergoing cardiac surgery developed acute FS at 12 weeks. Patients with ischaemic heart disease, and hyperlipidaemia, and who did not engage in regular post-op physiotherapy were at high risk of developing acute FS.
Spontaneous intracerebral haemorrhages from a Sri Lankan tertiary care center: 5-year data
(Ceylon College of Physicians, 2021) Dep, W.D.C.; Deelaka, A.G.S.; Somaratne, K.G.S.K.; Meegahapola, H.; Premadasa, H.M.S.D.; Kurukulasuriya, S.A.F.; Mettananda, K.C.D.; Ranawaka, U.K.
Introduction and Objectives Epidemiological data on spontaneous intracerebral haemorrhage (sICH) is limited from South Asia. We sought to describe epidemiology of sICH in a Sri Lankan cohort. Methods We studied all patients with stroke admitted to the Stroke Unit, Colombo North Teaching Hospital over five years. Data from sICH patients regarding treatment seeking delays, clinical char-jcteristics, risk factors, stroke severity and functional outcome were compared with ischa-mic stroke (IS) patients. Resists 984 patients (mean age 58.7 years; 62.1% males) were studied: sICH 15.0% (147 patients), IS 85.0%. sICH patients: mean age 58.0 years; 67.3% males. sICH patients presented to hospital earlier (<3h sICH 70.6%, IS 37.2%, p<0.001) and had more severe strokes (NIHSS>15) (sICH 21.3%, IS 12.2%; p<0.001). Hypertension was commoner in sICH group (sICH 72.6%, IS 63.5%; p=0.034), whereas diabetes (sICH 39.0%, IS 51.6%; p=0.005) and smoking (sICH 16.6%, IS 25.5%; p=0.021) were less common. Altered consciousness (sICH 30.3%, IS 18.3%; p=0.001), dysphagia (sICH 55.9%, IS 34.4%; p<0.001), bladder involvement (sICH 56.6%, IS 28.7%; p<0.001), and seizures (sICH 4.1%, IS 1.5%; p=0.029) were commoner among sICH patients. sICH patients had more severe disability on discharge (Barthel index 0-60: sICH 71.1%, IS 45.2%; p<0.001; modified Rankin scale (mRS) 3-6: sICH 76.7%, IS 52.1%; p<0.001). sICH location (lobar vs. deep) and presence of intraventricular haemorrhage was not associated with stroke severity. Lobar ICHs had more severe disability on discharge (Barthel index <60: p=0.037; mRS>3: p=0.020). On logistic regression, sICH was independently associated with early presentation to hospital (OR 1.79; p=0.039), and severe disability on discharge (Barthel index <60: OR 2.42, p=0.028; mRS>3: OR 2.70, p=0.012). Conclusions sICH patients sought medical attention early and had different clinical profiles, more severe strokes and more severe disabilities.