Browsing by Author "Luke, N.V."

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Possible gasoline-induced chronic liver injury due to occupational malpractice in a motor mechanic: a case report
(BioMed Central, 2017) Gunathilaka, M.L.; Niriella, M.A.; Luke, N.V.; Piyarathna, C.L.; Siriwardana, R.C.; de Silva, A.P.; de Silva, H.J.
BACKGROUND: Hydrocarbon-induced occupational liver injury is a well-known clinical entity among petroleum industry workers. There are many types of hydrocarbon exposure, with inhalation being the most common. Hydrocarbon-induced occupational liver injury is a rarely suspected and commonly missed etiological agent for liver injury. We report a case of a non-petroleum industry worker with chronic liverdisease secondary to hydrocarbon-induced occupational liver injury caused by chronic low-grade hydrocarbon ingestion due to occupationalmalpractice. CASE PRESENTATION: A 23-year-old Sri Lankan man who was a motor mechanic presented to our hospital with decompensated cirrhosis. He had been chronically exposed to gasoline via inadvertent ingestion due to occupational malpractice. He used to remove gasoline from carburetors by sucking and failed to practice mouth washing thereafter. On evaluation, he had histologically proven established cirrhosis. A comprehensive history and workup ruled out other nonoccupational etiologies for cirrhosis. The patient's long-term occupational gasoline exposure and clinical course led us to a diagnosis of hydrocarbon-induced occupational liver injury leading to decompensated cirrhosis. CONCLUSIONS: Hydrocarbon-induced occupational liver injury should be considered as a cause when evaluating a patient with liver injurywith possible exposure in relevant occupations.
Recurrent posterior reversible encephalopathy syndrome in a patient with focal segmental glomerulosclerosis: A case report
(EDORIUM Journals, 2016) Luke, N.V.; Wickramasinghe, S.S.; Ranawaka, U.K.
Introduction: Posterior reversible encephalopathy syndrome (PRES) is a rare clinical syndrome of which the aetiology and pathogenesis still remain unknown. We present a rare case of recurrent PRES in a patient with adult onset nephrotic syndrome due to focal segmental glomerulosclerosis (FSGS). Case Report: A 30-year-old Asian female with FSGS on renal biopsy developed two episodes of PRES with residual neurological deficits without significant hypertension. Both these episodes were preceded by initiation of treatment with calcineurin inhibitors for persistent proteinuria. She was subsequently started on mycophenolate mofetil without further recurrences of PRES. Conclusion: Although PRES is well recognized, this case has a combination of several unusual features that merit special attention.
Septicaemia caused by Elizabethkingia-sp in a 'healthy' Sri Lankan man
(London : Sage, 2018) Sebastiampillai, B.S.; Luke, N.V.; de Silva, S.T.; Premaratna, R.