Browsing by Author "Nilmini, R.R.P.S."

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Determination of metal content in Rasna Sapthaka Kwatha
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Abeysingha, W.A.M.U.S.; Nilmini, R.R.P.S.; Rajapakse, C.S.K.; Weerasooriya, W.M.B.
Rasna sapthaka kwatha is a widely used Ayurvedic decoction. Medicinal plants that are the ingredients of this decoction are collected from different habitats of the country. The decoction can be contaminated with metals during the growing, collecting, and storing of the raw material and also during the processing of this product. Hence, the evaluation of metal concentration in pharmaceutically available decoction is of utmost significance. Therefore, the main objective of this research was to determine the concentration of Al, Cr, Cd, Cu, and Pb in decoction samples of Rasna sapthaka kwatha collected from different areas of Sri Lanka. Ten samples of decoction were randomly collected from Anuradhapura, Kurunegala, Kandy, Polonnaruwa, Thambuththegama, Galadiulwewa and Gampaha. Atomic Absorption Spectrometry was used to detect the metal concentration. Wet digestion was carried out prior to the analysis. The mean concentration value of Al, Cd, Cr and Cu were 1.010ppm, 0.232 ppm, 0.387 ppm and 0.155 ppm respectively. Pb was below the detected level of the instrument. Al, Cd, Cr and Cu contents in decoction samples were found in the range of 0.39-2.208 ppm, 0.18-0.348 ppm, 0.33-0.462 ppm, and 0.042-0.408 ppm respectively. Results revealed that the mean values of metal concentration of tested samples were below the recorded WHO permissible level of metals in herbal medicine.
Effect of Herbal Formula in Rajaushadhanidhiya on Pityriasis Versicolor.
(Expanding Horizons through Research, Innovation & Communication, Rajarata International Research Conference – 2019, Rajarata University of Sri Lanka, 2019) Nilmini, R.R.P.S.; Dissanayake, K.G.C.
Skin diseases are common in society. Pityriasis versicolor is such skin disease that produces well demarcated round or oval macules on the trunk, neck, and upper arms where the density of sebaceous glands is high, appear as hyper-pigmented patches on lighter skin types and hypo-pigmented patches on darker or tanned skin and can vary in colour. There are many treatments in Ayurveda, to relieve Pityriasis versicolor. The formula used for the present study is an external application, mentioned in Rajaushadhanidhiya, however, the effects are not scientifically proven. The present study was aimed at finding the effcacy of this herbal formula composed of Ipomoea obscura, Curcuma longa, Cassia fistula, Phyllanthus emblica. This treatment is practiced in Ayurveda as a safe and effective external mode of therapy. Thirty patients were recruited for the study and were advised to consume the test formula for one month without using any other treatment for Pityriasis versicolor. The size, colour, clinical form, itching of affected areas were graded by the all researchers before and after the treatment. Data were analyzed using Statistical Package for the Social Sciences (SPSS) and Microsoft Excel. A significant (P value ≤ 0.05) reduction in size, itching, colour and clinical form of affected areas was observed after the treatment. It can be concluded that the tested herbal formula has a marked effect on reducing the symptoms of Pityriasis versicolor.
Evaluation of the herbal formula mentioned in Rajaushadhanidhiya in the management of Pityriasis Versicolor
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Nilmini, R.R.P.S.; Dissanayake, K.G.C.
Pityriasis versicolor is a common skin condition that produces well demarcated round or oval macules on the trunk, neck, and upper arms where the density of sebaceous glands is high. These lesions often appear as hyper-pigmented patches on lighter skin types and hypo-pigmented patches on darker or tanned skin and can vary in color. There are many treatments in Ayurveda, to relieve Pityriasis versicolor. The formula used for the present study is an external application, mentioned in Rajaushadhanidhiya; however, the effects are not scientifically proven. The present study aimed at finding the efficacy of this herbal formula composed of Ipomoea obscura, Curcuma longa, Cassia fistula, Phylenthes emblica. Thirty patients were recruited for this study and fifteen patients were advised to apply herbal formula and for others Nimbhadilepa for one month without other treatments for Pityriasis versicolor. The size, colour, clinical form, itching of affected areas were graded by the researchers before and after the treatment. Data were analyzed using Statistical Package for the Social Sciences (SPSS) and Microsoft Excel. A significant reduction (p value <0.05) in size, itching, colour and clinical form of affected areas was observed after the treatment in Test group. Although P value<0.05 in size and itching of affected areas, P value>0.05 in colour and clinical form in control group. It can be concluded that the tested herbal formula has a better effect than Nimbhadilepa on reducing the symptoms of Pityriasis versicolor.