Browsing by Author "Pathirana, D."
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Item An Atypical case of Kawasaki disease presenting with cholestatic jaundice(Sri Lanka College of Paediatricians, 2015) Perera, P.J.; Samarasinghe, D.A.; Pathirana, D.; Randeni, S.; Samdamal, L.Y.S.Case Report, No abstract available.Item Factors associated with general health status and general wellbeing of Advanced Level students in the Colombo district, Sri Lanka(Faculty of Medicine, University of Kelaniya, Sri Lanka, 2021) Gangodawila, T.; Isurika, A.; Pathirana, D.; Katugampala, M.; Rupasinghe, T.; Nazeer, I.; Hettiaratchi, U.Introduction: Adolescents need to maintain a good general health status and well-being since they are at a developmental stage of life. Objectives: To describe factors associated with General Health Status (GHS) and General Well Being (GWB) of Advanced level(A/L) students in the Colombo district. Methods: A descriptive, cross-sectional study was conducted using a self-administered questionnaire (Google form), among 480 A/L students using convenient sampling technique. GHS and GWB were measured using PedsQL 3.0 General wellbeing module (validated questionnaire). GHS was given a score of 0-4. GWB was assessed by six questions which was scored on Likert scale. Overall percentage scores were calculated for both GHS and GWB. Data were analysed using SPSS Version 26. Associations were obtained using independent t test (p< 0.05-significant). Results: GHS was poor (score-0) in 5.4%. GHS was significantly associated with income, meal skipping and sufficiency of physical activities. Mean GHS score of low-income group (43.6) was higher than high-income group (38.7). Students who had not skipped meals had obtained higher GHS scores for all three meals (breakfast: 44.2, lunch: 42.4, dinner: 43.5) compared to students who skipped meals (36.5, 37.4, 36.5). Students who sufficiently engaged in physical activities (60mins/day) had higher GHS score (51.3) than the others (39.0). GWB score was 76-100% in 45.6%. A significant association was observed between nutritional adequacy of diet and GWB. Mean GWB score was high (76.4) in students who were consuming a nutritionally adequate diet compared to others (70.2). Conclusions: GHS was poor in 5.4%. Excellent GWB was reported. Low income, not skipping meals and sufficient physical activities were associated with good GHS. Nutritional adequacy was associated with good GWB.Item Neonatal septicaemia : the incidence, symptomatology and microbiology(Sri Lanka Medical Association, 1998) Karunasekera, K.A.W.; Pathirana, D.; Alwis, L.W.G.R.INTRODUCTION: The awareness of incidence and aetiology of septicaemia plays an important role when implementing preventive measures. The identification of offending organism helps to guide the initial antibiotic therapy which should be started immediately as the progression of early symptoms to death could occur in less than 24 hour. OBJECTIVES : To assess incidence and to identify' clinical presentations and offending organisms of neonatal septicaemia. METHODS : This study was carried out in the University Paediatric Unit, Colombo North Teaching Hospital Ragama from January to December 1996. Neonates with positive blood cultures and those having septicaemia clinically with negative blood cultures were included in the study. Data was analysed by Epilnfo version 6. RESULTS : 98 babies were diagnosed to have septicaemia during the study period. The incidence of septicaemia in the University Obstetric Unit was 24.4 per 1000 livebirths (98 out of 3851 live bom babies) and the case fatality rate was 11.2%. The incidence was significantly higher in babies with low birth weight (LBW) and in those born following instrumental delivery (p<0.01). 21.4% of babies developed septicaemia on first day of life, 74.5% between 2-7 days and 4.1 % after first week. The common presenting features were fever 61.2%, jaundice 52%, lethargy 37.8%, refused feeding 25.5%, coffee grounds vomiting 22.4% and fits 12.2%. The common bacteria identified were Klebsiella 29.2%, Staphylococcus aureus 16.9%, E.coli 5.6%, Coliform bacilli which could not be identified further 13.5% and non haemolytic streptococci 8.2%. The common sensitive antibiotics were Amikacin 88.9%, Amoxycillin + ClavuL'oic acid 183%, Ceftriaxone 78.1%, Netilmicin 63.9%, Gentamicin56.4% and Ceftazidime55.2%. CONCLUSIONS : This study shows that septicaemia is an important cause of morbidity in babies w ith LBW and those with instrumentation at birth. Our study confirms the nonspecific presentation of septicaemia. The finding of high incidence of late septicaemia and septicaemia due to Klebsiella and Staph. aureus indicates that most babies acquired it from the hospital.Item A Preliminary study on neonatal septicaemia in a tertiary referral hospital paediatric unit(Sri Lanka Medical Association, 1999) Karunasekera, K. A. W.; Pathirana, D.