Browsing by Author "Ranasinghe, R.H.S."

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The efficacy of Rakta Apamargadi Dhooma Varti in the management of Nasa Arsha (Nasal polys).
(Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka, 2017) Ranasinghe, R.H.S.; Peiris, K.P.P.
Nasal Polyps represent a challenging diagnosis for the physician to treat. Management of nasal polyps forms a large part of the workload due to non-availability of successful treatment modalities with reincarnation of removed polypoidal tissues. Among Ayurvedic treatments, fumigation treatment (Dhoopana Kalpana) was used in the management of Nasa Arsa. This study aimed at introducing a new treatment modality with new formulation Rakta Apamargadi Dhooma Varti. It has been practiced clinically in Shalakya clinic at Gampaha Wickramarachchi Ayurveda Hospital, though not statistically evaluated. In the clinical study, 20 patients were selected in age group between 16-60 years irrespective of their sex, religion, occupation and habitat etc. They were randomly divided in to two groups and a detailed research performa was prepared incorporating all the relevant points to study the patient as well as the disease. Group A was treated with Rakta Apamargadi Dhooma Varti for fumigation treatment with Thamalakyadi Phanta and Seetarama Vati. Group B was treated with above internal medicine without fumigation. All of them completed the treatment accurately within two weeks and the follow up study continued up to one month. After the treatment, the size of the Nasa Arsha was assessed on the basis of the anterior rhinoscopic examination with pre and post photographs and by assisting special symptom wise questionnaire, Nasal Obstruction Symptom Evaluation (NOSE) instrument/scale with visual analogue scale and tested blood for WBC/DC levels as special investigation. According to the analysis, fumigation treatment had shown signicant results for nasal obstruction and reducing the size of the polypoidal sprouts. However, while considering the other symptoms such as headache, running nose, sneezing and itching of eyes Group B too has shown considerable improvement.
Traditional Sri Lanakan Spices for Dyslipidemia, International Journal of Scientific and Research Publications
(International Journal of Scientific and Research Publications, 2020) Dissanayake, K.G.C.; Liyanage, R.P.; Ranasinghe, R.H.S.
Sri Lanka is a country where has efficacious food cultures related to their traditional life styles. In traditional food recipes native spices such as Garcinia cambogia or Garcinia zeylanica (Goraka or Malabar Tamarind), Tamarindus indica (Siyambala or Tamarind), Piper nigrum (Gammiris or Pepper), Trigonella foenum-graecum (Uluhal or fenugreek) and Cinnamomum zeylanicum (Kurundu or Cinnamon) are enriched. Recent advances in global perspectives on non-communicable diseases reconsidering traditional foods including spices for health prevention and promotion. Therefore, the current study aims to review ethnomedicinal value of aforementioned spices considering its biochemical effect on lipid profile including total cholesterols, triglycerides, low density lipoproteins and high density lipoproteins at cell biology and effect on biochemistry in cellular level. The study was designed as a literature review through primary and secondary literature sources which are available online with utmost attention to peer reviewed and indexed journal articles. Thirty articles were considered as references while reviewing fifty two related research studies. Biochemical modifications in cellular sites relevant to management of serum lipid values were identified in each of spices. Biochemical effect on lipogenesis and lipid metabolism in each variety were identified. The study suggests that the consumption of spices is beneficial in lipid level management.