Browsing by Author "Senevirathna, N."

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Relationship between angina and physical activity to the Quality of Life (QOL) of patients following Coronary Artery Bypass Graft (CABG)
(Research Symposium on Pure and Applied Sciences, 2018 Faculty of Science, University of Kelaniya, Sri Lanka, 2018) Aberathna, A. M. I. S.; Danasekara, D. R. S. R.; Wickramarachchi, W. A. T. R.; Jayathissa, S. N. E.,; Bandara, S. M. K. B.; Karunaratna, N. G. K. D.; De Silva, H. M. Y. R.; Senevirathna, N.; Wijesinghe, R. A. N. K.
Coronary artery disease has been identified as the most common cardio vascular disease. Prevalence of coronary artery disease is on the rise in Sri Lanka resulting in high hospital admission, morbidity and mortality. Coronary artery bypass graft surgery is one of the major treatment procedures in coronary revascularization. The main goals of coronary artery bypass graft include improving chance of survival, improving quality of life to resume an active life style and reducing angina. An individual’s quality of life is defined as general wellbeing and negative and positive features of life. This study was conducted to find out the relationship between angina and physical activity to the quality of life in patients after coronary artery bypass graft. This was a descriptive cross sectional study of 90 patients after coronary artery bypass graft 9 to 15 months following the surgery who attended cardiology and cardiothoracic clinics at Sri Jayawardhanapura General Hospital. Data was collected via quality of life questionnaire, six-minute walk test and Canadian cardiovascular society grading of angina pectoris. Quality of life was measured by using self-administered Nottingham Health Profile questionnaire and the Canadian cardiovascular society grading of angina was used to evaluate the angina grade of the patient. Six-minute walk test was performed by each patient under close observation of the interviewer. Patients with angina grade I had a good quality of life (Nottingham health profile score 0-0.26) in 61.2% and poor quality of life (Nottingham health profile score  0.27) in 38.8%. Patients with angina grade II had a good quality of life in 36.6% and poor quality of life in 63.4%. Hence there is a significant association between poor quality of life and angina grade II (p=0.02). The physical activity after the coronary artery bypass graft was measured through the performance of average percentage of six-minute walk test ( 50% poor performance and 51% good performance). Patients with good physical activity (51% performance in sixminute walk test) had good quality of life in 54.2% and poor quality of life in 45.8%. Patients with poor physical activity ( 50% performance in six-minute walk test) had good quality of life in 33.3% while poor quality of life in 66.7%, even though the six-minute walk test was found not to be significantly associated with quality of life (p=0.114). Furthermore, a relationship was found between angina grade and physical activity (p=0.002).
Thinness negatively affects lung function among Sri Lankan children
(Public Library of Science, 2022) Senevirathna, N.; Amarasiri, L.; Jayamanne, D.; Manel, K.; Liyanage, G.
Background: There have been conflicting findings on the effect of body mass index (BMI) on lung functions in children. Therefore, we studied the relationship between spirometry parameters and BMI among healthy Sri Lankan school children aged 5-7 years. Methods: A cross-sectional study was conducted among 296 school children (5-7-year-old) without apparent lung disease. Recruitment was done with stratified random sampling. Spirometry parameters, FEV1, FVC, PEFR, and FEV1/FVC ratio were determined. The acceptable and reproducible spirometry recordings were included in the analysis. Simple and multivariate linear regression analysis examined possible associations of lung function parameters with BMI, socio-demographic variables and indoor risk factors. Also, the mediator effect of gender on lung function through BMI was explored. Results: The participants' mean age (SD) was 6.4 (0.65) years. One-third were thin/severely thin (37%). A statistically significant difference in FVC (p = 0.001) and FEV1 (p = 0.001) was observed between BMI groups (obesity/overweight, normal, and thinness). Yet, PEFR or FEV1/FVC did not significantly differ among BMI groups (p = 0.23 and p = 0.84). Multivariate regression analysis showed that FEV1 and FVC were significantly associated with BMI, child's age, gender, family income, father's education, having a pet, and exposure to mosquito coil smoke. Interaction between gender and BMI for lung functions was not significant. The thin children had significantly lower FVC (OR: -0.04, 95%CI: -0.077, -0.012, p = 0.008) and FEV1 (OR: -0.04, 95%CI: -0.075, -0.014, p = 0.004) than normal/overweight/obese children. Family income demonstrated the greatest effect on lung functions; FVC and FEV1 were 0.25L and 0.23L smaller in low-income than the high-income families. Conclusion: Lower lung function parameters (FVC and FEV1) are associated with thinness than normal/overweight/obese dimensions among children without apparent lung disease. It informs that appropriate nutritional intervention may play a role in improving respiratory health.