Browsing by Author "Shifra, A.S.F."

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    Evaluation of anti–oxidant properties of a traditional formulae (JB Kalka).
    (Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka, 2017) Shifra, A.S.F.; Gunasekara, G.V.M.T.D.; Kularathna, M.D.C.N.; Cooray, P.L.J.U.D.; Perera, H.M.P.; Fernando, S.H.S.; Sadungama, M.K.N.G.; Thilakarathna, B.S.D.; Kuruppuarachi, S.N.; Kuruppuarachi, S.N.; Saranya, U.; Rishad, Y.M.; Kaluthotage, S.; Kularathne, D.A.B.H.; Umayanagni, L.H.S.
    Cancer is a group of diseases involving abnormal cell growth with the potential to invade to other parts of the body. In Ayurveda, cancer is dened in the term Arbuda, which is categorized by big, deep seated, immovable, round, slightly painful and slowly increasing Arbuda which is caused by penetration of increased Doshas into the body tissues and blood. In 2012, about 14.1 million new cases of cancer were reported globally and it caused 8.2 million or 14.6% of deaths. Though there are several advanced treatment strategies available in the management of cancer in modern medical system, most of them cause lots of side effects. But JB Kalka is a traditional preperation which is being successfully practiced by Kottayawatta generation in the management of cancer without any side effects. This formula was selected to demonstrate literature review of its all ingredients and to evaluate its anti-oxidant properties and physicochemical parameters. The JB Kalka was prepared according to the guidelines indicated by the traditional practitioners. The literature review of all ingredients was compiled from Ayurvedic classical texts, electronic databases of Google scholar, PubMed and through web search. As per literature review, JB Kalka has properties of Katu- Thiktha- Kasaya Rasa, Laghu- Theekshana Guna, Ushna Veerya and Katu Vipaka which regulate Thridoshas by pacifying Kapha and Vata and increasing Pitta. This study shows an anti-oxidant properties of JB kalka according to DPPH method by colour change from purple into pale yellow. According to the quantitative test, methanolic extract of JB Kalka exhibited highest potential for DPPH radical scavenging activity as it had the least IC50 value of around 1.25 mg/ml. Therefore, JB Kalka is an effective medicinal preparation to be used in the tratment of cancer as an anti-cancer drug. But further studies with large sample should be carried out to scientically justify the effectiveness of JB Kalka in the management of cancer and to identify an immune modulatory, cyto toxic and anti-cancer properties of JB Kalka.
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    Irsal e alaq (Hirudo therapy) on Maa e Aksar (glaucoma): a scientic review.
    (Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka., 2017) Shifra, A.S.F.; Ayshah Fazeenah, A.H.
    Maa e aksar (glaucoma) is caused by either increased production or reduced absorption of rutubat (uid) which makes an accumulation inside the eye ball that produces tanao (tension) and constructs the eyeball hard. It results in zoa'f e basar (weakness of vision) and maidan e basarat (narrowing of visual eld). This condition corresponds with glaucoma in allopathic medicine and is dened as a group of conditions characterized by typical changes in the retinal nerve bers and optic nerve head resulting in reduced visual eld, progressive and irreversible vision loss. Its enormous social and economic impact can be acceptable by the fact that it remains as the second leading cause of blindness globally, after cataracts. In 2013, the number of people aged 40-80 years with glaucoma worldwide was estimated to be 64.3 million, increasing to 76.0 million in 2020 and 111.8 million in 2040. Mostly, glaucoma is asymptomatic; generally patients may have complaints like blurred vision, hardness to see in dark, tearing, soreness / tiredness, pain in the affected eyes or frontal portion of the head, feeling of something in the eye and observing the rainbow halos around the light. The treatment is in contrast to nature and Mizaj (temperament) of the disease. Therefore, the elimination of the root cause is the main treatment modality. Despite the use of numerous newer therapeutic regimens, it has remained confronted because of waning of the sensitive part of the eye. The holistic approach of Unani treatment will have a thriving management of diseases with temperamental afliation and its evidences were found throughout the history. Irsal e Alaq (hirudo / leech therapy) which is one of the most important and widely practiced methods used for local evacuation of morbid (invalidated and waste) matter with the use of medicinal leech, has proven efcacy in Maa e aksar, but lacks scientic evidence for validation. The present literary review was based on Unani classical texts, electronic databases of Google scholar, PubMed and through web search. This review aims at highlighting the concept of glaucoma with special reference to Maa e aksar and its management through Irsal e Alaq.