Browsing by Author "Sugataratana, K."

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    Correlation of Dementia with Smrutibhramsa mentioned in Ayurvedic Mental disease: A review.
    (International Conference on Sanskrit Studies, 2017 Department of Sanskrit, University of Kelaniya, Sri Lanka., 2017) Karunaratne, T. D. N.; Sugataratana, K.; Ariyawansa, H. A. S.; de Silva, H. A.
    Dementia is a chronic brain disease it combination of several symptom that are associated with the declining abilities of the brain and its’ functions.There may be a decline in thinking, memory, cognition, language skills, understanding and judgment. Memory impairment is the main symptomand senile age is a biggest risk factor for Dementia. There is no definite comparison of Dementia with ayurveda Mānasarāga paradigm. Aim of this endeavor is to correlate dementia in modern medicine and Smrithibramsa mentioned in Ayurveda.This is a literal review article gathering information from, authentic Ayurveda Sanskrit texts, journals and web sources. It is revealed that there is no definite pattern of classification of Mānasarāga in Ayurvedic Sanskrit texts. Description of Mānasarāga is found in scatted form at different places in Sanskrit texts of Ayurveda. In Ayurveda literature has clearly mentioned thatin Caraka Samhitha Sharirasthana, impairment of memory as Smrutibhramsa which occurs due to a person being overcome by rajas and Tamas Dosās in the mind.Aging is describe in Ayurveda term as Kalajara. So memory impairment of aged can say as Jarājanyasmrutibhramsa” in Ayurveadic point of view. Memory impairment is predominant symptom in dementia as well as Smrutibhrams According to the data age is the biggest risk factor for dementia and Smrutibhramsa. In coclution: there are co-relationsof dementias with Smrutibhramsa
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    Standardization of sarasvatha choorna: used as a remedy for Dementia
    (Science publishing Group, 2015) Karunaratne, T.D.N.; Sugataratana, K.; Ariyawansa, H.A.S.; de Silva, H.A.; Samarasingha, K.; Arawwawala, L.D.A.M.
    Sri Lanka has been recognized as one of the fastest aging populations from the developing countries. There is a large senior population in the country. Since age is the biggest risk factor for Dementia, the need to create awareness and management is an increasing necessity. Sarasvatha Choorna is one of the polyherbal preparation used in Ayurveda for the management of Dementia which consists of 12 medicinal plants. In the present study, an attempt was made to standardize Sarasvatha Choorna by using standard protocols. Standardization was carried out by determination of total ash, water soluble ash, acid insoluble ash, microbial counts, heavy metals, phytochemical screening and development of TLC-densitogram fingerprints. Results revealed that 10.6±0.0% of total ash, 8.4±0.0% of water soluble ash 0.65±0.01% of acid insoluble ash 11.0±0.1% of cold ethanol extractable matter, 13.9±0.1% hot ethanol extractable matter, 13.9±0.1% cold water extractable matter and 20.2±0.2% hot water extractable matter were present in the Sarasvatha Choorna. Pathogenic microorganisms such as Coliforms, Escherichia coli and Salmonella were not found and heavy metal concentrations of Sarasvatha Choorna were well below the recommended upper limits for the tested heavy metals. Phytochemical screening studies revealed the presence of flavonoids, steroid glycosides and coumarins in both water and ethanol extracts of Sarasvatha Choorna. Presence of the raw materials in the Sarasvatha Choorna was confirmed by TLC fingerprints. Present study reveals the quality of Sarasvatha Choorna for the first time and quality control parameters resulted from this study can be used as a reference standard for quality control of Sarasvatha Choorna.