Chemistry
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Item Permetalated Aromatic Compounds(Comments Inorganic Chemistry, 1996) Winter, C.H.; Senevirathne, K.N.; Bretschneider-Hurley, A.Item Synthesis, Spectroscopic Characterization and Reactivity of Ruthenocene Bearing Pentamagnesiated Cyclopentadienyl Ligands(Journal of American Chemistry Society, 1996) Senevirathne, K.N.; Bretschneider-Hurley, A.; Winter, C.H.Item Synthesis, Reactivity, and Characterization of Ruthenocene Bearing Pentazincated Cyclopentadienyl Ligands(Organometallics, 1997) Senevirathne, K.N.; Winter, C.H.Item Endotoxin induced production of interleukin-6 is enhanced by vitamin E deficiency and reduced by black tea extract(inflamm research, 1995) Amarakoon, A.M.; Tappia, P.S.; Grimble, R.F.Studies were performed to investigate the effect of a polyphenol rich extract from black tea and vitamin E on bacterial lipopolysaccharide (endotoxin) induced IL-6 production, alterations in liver glutathione and antioxidant acute phase protein (caeruloplasmin) concentration, in rats fed on a synthetic diet for 21 days. In the vitamin E sufficient group a significantly lower IL-6 concentration than in vitamin E deficient animals was observed. Addition of tea extract to the diet produced a similar reduction in IL-6, but no synergism occurred in the presence of both vitamin E and tea extract. However, a significantly lower caeruloplasmin and a significantly higher liver glutathione concentration was observed in rats fed both substances. It is suggested that consideration of dietary components which alter antioxidant/oxidant status may contribute towards treatment of inflammatory/autoimmune diseases.