Medicine
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This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty
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Item Short-chain fatty acid irrigation in severe pouchitis(Massachusetts Medical Society, 1989) de Silva, H.J.; Ireland, A.; Kettlewell, M.; Mortensen, N.; Jewell, D.P.No Abstract availableItem The Association of autoimmune disorders with inflammatory bowel disease(Oxford University Press, 1989) Snook, J.A.; de Silva, H.J.; Jewell, D.P.Medical records of patients with ulcerative colitis (n = 858), Crohn's disease (n = 378) and coeliac disease (n = 148) were examined to determine the prevalence of associated autoimmune disorders. Of outpatient controls (n = 300), 2 per cent had at least one autoimmune disorder, compared to 7 per cent with ulcerative colitis, 2 per cent with Crohn's disease and 6 per cent with coeliac disease. Inclusion of primary sclerosing cholangitis with the autoimmune disorders increased the overall prevalence in ulcerative colitis to over 9 per cent. The results provide further indirect evidence of involvement of autoimmune mechanisms in the pathogenesis of ulcerative colitisItem Skeletal muscle necrosis in severe falciparum malaria(British Medical Association, 1988) de Silva, H.J.; Goonetilleke, A.K.; Senaratna, N.; Ramesh, N.; Jayawickrama, U.S.; Jayasinghe, K.S.; Amarasekera, L.R.No Abstract AvailableItem Sero-negative rheumatoid arthritis in haemoglobin E thalassaemia(Sri Lanka Medical Association, 1988) de Silva, H.J.; Senaratne, N.L.; Goonetilleke, A.K.; de Silva, C.; Jayawickrama, U.S.; Amarasekera, L.R.No Abstract AvailableItem Endoscopic sclerotherapy for oesophageal variceal bleeding(Sri Lanka Medical Association, 1988) de Silva, H.J.; Samarasekera, D.M.; Amarasena, C.; Fernando, D.P.No abstract availableItem A Self-limiting midline cerebellar syndrome. Is falciparum malaria the cause?(Sage Publishing, 1988) de Silva, H.J.; Gamage, R.; Herath, H.K.; Peiris, J.B.; Abeysekera, D.T.No Abstract AvailableItem Erythema induratum (of Bazin) in a patient with endometrial tuberculosis(BMJ Publishing Group, 1988) de Silva, H.J.; Goonetilleke, A.K.; de Silva, N.R.; Amarasekera, L.R.; Jayawickrama, U.S.We report erythema induratum in a patient who was found to have active endometrial tuberculosis. This case report emphasizes the importance of an exhaustive search for active tuberculosis in patients with erythema induratum, especially in countries where tuberculosis is prevalent, as the indiscriminate treatment of erythema induratum with steroids may be harmfulItem Delayed cerebellar ataxia: a new complication of falciparum malaria?(British Medical Association, 1987) de Silva, H.J.No Abstract AvailableItem Multiple lentigenes syndrome--a case report(Sri Lanka Medical Association, 1987) de Silva, H.J.; Dharmadasa, K.; Nadarajah, M.No abstract availableItem The Treatment of Guillain-Barre syndrome by modified plasma exchange--a cost effective method for developing countries(BMJ Publishing Group, 1987) de Silva, H.J.; Gamage, R.; Herath, H.K.; Karunanayake, M.G.; Peiris, J.B.Six patients with the Guillain-Barré syndrome were treated by modified plasma exchange. Five of them showed a rapid improvement which was not consistent with the natural history of the disease. The improvement was assessed by monitoring vital capacity and muscle power, grading the ability to perform motor functions and by the duration of the hospital stay. The method of plasma exchange we used was simpler and cheaper than the conventional method. We recommend the use of our method, especially in developing countries with financial constraints and poor facilities.