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End date: 2019Subject: search.filters.subject.Siddha medicine

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    Study of acute and 28 days repeated oral toxicity of Siddha formulae Seenthilchooranam in Wistar albino rat.
    (Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka, 2017) Ushakanthan, S.; Visweswaran, S.; Sivakkumar, S.; Mariyappan, A.; Banumathi, V.
    Seenthil Chooranam is one of the traditional Siddha formulae used in various kinds of diseases in Siddha system of medicine. The test drug Seenthil Chooranam (Chooranam-one of the 32 types of internal medicine), mentioned in classical Siddha text Agasthiyar Paripuranam – 400, is used for Megam (diabetic mellitus), Eelai (tuberculosis), Kasam (cough), Elaipu (bronchial asthma),Erandavayu (scrotal swelling). The ingredients of this formulae include Seenthil (Tinosporacordifolia), Karisalai (Eclipta Alba), and Earthworm (Eudriluseugeniae). The present studyaimed at evaluating the safety of Seenthil Chooranam as per OECD Guidelines 423,407. This study focused on acute and repeated dose 28 days oral toxicity studies in wistar albino rat. In acute study, Seenthil Chooranam was administered orally at the dose of 2000mg/kg. b.w and animals were observed for toxic signs for a period of 14 days. In repeated dose 28 days oraltoxicity study, Seenthil Chooranam was administered at the dose of 900mg and 1800mg/kg b.w.Mortality, toxic signs, body weight, food and water consumption, haematological, plasma biochemical parameters, gross necropsy, relative organ weights and histopathology were assessed. The results of these studies revealed that the drug Seenthil Chooranam did not produce any death at the dose of 2000mg/kg body weight. The LD value is greater than 2000mg/kg body 50weight. Repeated dose 28 days oral toxicity study was observed without any abnormalities and No-Observed Adverse Effect Level (NOAEL) was noted. It conrms the safety of the drug which proved its utility in long term administration without any harm to the human being.
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    A Siddha review of fi stula.
    (Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka, 2017) Tharshanodayan, N.J.Q.; Rohini, P.
    Fistulas were formerly associated with considerable mortality rates. The World Health Organization (WHO) estimates that there are 50,000-100,000 new cases of stulas every year. The three humours maintain the upkeep of the human body through their combined functioning and when deranged they bring about peculiar effects. Siddha system of medicine can create great hope for controlling the stula. It is considered that many such diseases have multiple etiologies; hence a multipronged approach is more suitable in their management. A detailed description about Pakanthiram is present in ancient Siddha texts “Pararagasasegaram” and “Siddhar aruvai maruththuvam” with symptomatology, their curative and preventive measures. This review explains the basic understanding and description of pakanthiram (stula), symptomatology of which resembles with symptoms of stula and, classication of Pakanthiram. Data was collected from 'Pararasasegaram' and 'Siddhar Aruvai Maruththuvam' about 'Pakanthiram' related to modern aspect. The data was analyzed in terms of allopathic system. 'Pararaasa Seagram' has classied stula in to six major groups; Moola Pavunthiram, Suroni Pavunthiram, Yoni Pavunthiram, Pavunthira Odu, Thaarai Pavunthiram and Vilai Pavunthiram. The rst four major groups have been related to the perennial region. Thaarai Pavunthiram is concerned with artery and vein. Finally, Vilai Pavunthiram has been related to the intracranial space and upper spinal cord. The relationship between the ancient Siddha medicine sagacity and modern classication of stula bears striking similarities.
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    Influence of Tamil language on indigenous medicine in Sri Lanka
    (Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Sri Lanka, 2016) Peiris, R.M.; Samaratunga, U.; Kaldera, H.P.I.J.; Wewalwala, S.L.
    The indigenous medicine of Sri Lanka claims an archaic practice tracing its roots back to pre-Aryan civilization with a cultural heritage comprised of indigenous wisdom, religious concepts of Buddhism, knowledge of Siddha medicine and Ayurveda. The absorption of Ayurveda and Siddha medicine into indigenous practice was itself a historical event. These systems were gifted from India along with several waves of culture that passed over to us. Authentic indigenous medical texts have proven that the foreign remedies have been absorbed into indigenous medicine through the various nations migrated to Sri Lanka. This study was carried out to find out the influence of Tamil language on indigenous medicine. Vatikaprakarana, Ayurveda Pharmacopoeia, the book series ‘Talpate piliyam’, Deshiya Paribhashika Shabdakoshaya, Deshiya Cikitsa Samgrahaya, Vanavasa Nigantu, Sarasvathi Nigandu and Vaidya Chinthamaniya were used as the data sources in this study. The study revealed that the Southern Indian physicians who abided Sri Lanka between 17th and 18th century had written their remedies on Ola leaves in Sinhala language adhering to its pronunciation and some of them were written in their original Tamil form. Further, it was found that those words can be classified under different categories such as plant origin materials (Kuppameniya, Nochchela, Kuringnan), mineral origin materials (Sinakkaran, Elimarindu, Wellapashanam), diseases (Visappu, Vadan, Sanni), dosages (Manchadi, Mukkal, Kal) and preparations (Kulambu, Kayam). In addition, some Mantras used in traditional medicine also consisted of Tamil words. According to the study, it can be concluded that the findings mentioned in the studied indigenous texts explicate the influence of Tamil language on indigenous system of medicine in Sri Lanka.