Protective effect of vitamin E in kidney storage solution on renal tissue metabolism in rats

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dc.contributor.authorSelliah, S.en_US
dc.contributor.authorde Mel, T.en_US
dc.contributor.authorHewamadduma, C.A.A.en_US
dc.contributor.authorde Tissera, A.en_US
dc.creator.corporateauthorSri Lanka Medical Associationen_US
dc.date.accessioned2014-10-29T09:14:33Z
dc.date.available2014-10-29T09:14:33Z
dc.date.issued1995en_US
dc.descriptionIndexed in MEDLINE
dc.description.abstractOBJECTIVE:To determine whether inclusion of vitamin E into kidney storage solutions protects metabolism and tubular ultrastructure of stored rat kidney. METHODS: Rat kidneys were flush stored in Marshall's Citrate (MC) and MC + vitamin E (25% of LD 50 and 50% of LD 50) for 24 hours at 0 degrees C. After storage kidney slices were tested for gluconeogenesis and lactate dehydrogenase (LDH) activity, and examined for cellular ultrastructure. RESULTS: Kidneys stored in MC + vitamin E gave higher gluconeogenesis than those stored in MC alone (p < 0.001). Tubular ultrastructure was better preserved in the presence of Vitamin E. CONCLUSIONS: Vitamin E appears to protect the metabolism and ultrastructure of stored rat kidneys.
dc.identifier.citationThe Ceylon Medical Journal. 1995; 40(2): pp.97-100en_US
dc.identifier.departmentPhysiologyen_US
dc.identifier.issn0009-0875 (Print)en_US
dc.identifier.urihttp://repository.kln.ac.lk/handle/123456789/1252
dc.publisherSri Lanka Medical Associationen_US
dc.subjectGluconeogenesis-drug effects
dc.subjectKidney-metabolism
dc.subjectOrgan Preservation
dc.subjectVitamin E-pharmacology
dc.titleProtective effect of vitamin E in kidney storage solution on renal tissue metabolism in ratsen_US
dc.typeArticleen_US

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