Pharmacognosy and phytochemical study of Amalakayas Rasayana; an anti ageing Ayurvedic formulation
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Date
2010
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Journal of Ancient Medicine and Yoga
Abstract
Pharmacognostical study revealed that the ingredients of Amalakayas Rasayana are authentic.
Physicochemical parameters of AR are within the accepted range. The 30.6% w/w of total ash and acid
insoluble ash 3.45% w/w may be due to its iron (Fe2
O3
) content. AR contains 50% w/w water soluble
extractives, which indicates that AR is easily soluble in water. AR gives 2 and 6 spots on short and long UV
light respectively, which indicate that its chemical compounds are easily separable. AR contains 27.5% w/
w iron (Fe2
O3
) indicating it?s a good source of iron. The total phenolic content was given satisfactory linearity
against Gallic acid equivalents (R2
= 0.998). The DPPH (R2
=1 in polynomial plotting) assay showed good
linearity against ascorbic acid indicating its free radical scavenging activity. EDTA & NBT assays showed
sufficient linearity (R? = 0.976) against ascorbic acid indicating potent superoxide radical scavenging activity,
whereas ferrous reducing power was also showed satisfactory linearity (R? = 0.986). Total tannin was
estimated 2.82 % w/w. The extract was also showed ROS scavenging activities (R2
=0.976; EC50=77.5?g/ml).
These pharmacognostical, physic-chemical and analytical parameters will help to establish further standards
of Ayurvedic drugs to assure their safety, purity and efficacy.