Host gene expression analysis in Sri Lankan melioidosis patients.

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dc.contributor.authorKrishnananthasivam, S.
dc.contributor.authorJayathilaka, N.
dc.contributor.authorSathkumara, H.D.
dc.contributor.authorCorea, E.
dc.contributor.authorNatesan, M.
dc.contributor.authorDe Silva, A.D.
dc.date.accessioned2017-12-13T09:33:40Z
dc.date.available2017-12-13T09:33:40Z
dc.date.issued2017
dc.description.abstractMelioidosis is a life threatening infectious disease caused by the gram-negative bacillus Burkholderia pseudomallei predominantly found in southeast Asia and northern Australia. Studying the host transcription profiles in response to infection is crucial for understanding disease pathogenesis and correlates of disease severity, which may help improve therapeutic intervention and survival. The aim of this study was to analyze gene expression levels of human host factors in melioidosis patients and establish useful correlation with disease biomarkers, compared to healthy individuals and patients with sepsis caused by other pathogens.en_US
dc.identifier.citationKrishnananthasivam,S., Jayathilaka,N., Sathkumara,H.D., Corea,E., Natesan,M., De Silva,A.D. (2017) Host gene expression analysis in Sri Lankan melioidosis patients. PLoS Negl Trop Dis 11(6): e0005643. https://doi.org/10.1371/journal.pntd.0005643en_US
dc.identifier.urihttp://repository.kln.ac.lk/handle/123456789/18543
dc.language.isoenen_US
dc.publisherPLoS Negl Trop Dis 11(6)en_US
dc.subjectHost geneen_US
dc.subjectmelioidosis patientsen_US
dc.subjectpathogensen_US
dc.subjectbacillus Burkholderia pseudomalleien_US
dc.titleHost gene expression analysis in Sri Lankan melioidosis patients.en_US
dc.typeArticleen_US

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