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Item The Efficacy of Raktha Apamargadi Dhooma Varthi in the Management of Nasa Arsas (Nasal Polyps)(International Journal of Multidisciplinary Research and Development, 2019) Peiris, K.P.P.; Ranasinghe, H.N.K.P.; Samaranayake, G.V.P.Nasal Polyps represent a challenging diagnosis for the physician to treat. Management of nasal polyps forms a large part of the workload because the available treatment modalities having unsuccessful results with reincarnation of removed polypoidal tissues. Among the Ayurvedic treatments, fumigation treatment (Doopana Kalpana) was used for the management of Nasal polyposis. This study aimed to introduce a new treatment modality with new formulation, which named as Rakta Apamargadi dhooma varti. lt had been practiced clinically but not scientifically evaluated. In the clinical study 20 patients were selected between the age of 16-60 years irespective of their sex, religion, occupation & habitat etc. They were divided randomly by lottery method into two groups. Group A was treated with Rakta ,4pamargadi dhooma varti as local treatment with internal medicine and Croup B was treated only with internal medicine. Al1 the patients were completed the treatment and follow up study. According to analysis, fumigation treatment has been shown better result for nasal obstruction and reducing the size of the polypoidal sprouts. However, while considering the other symptoms, headache, running nose, sneezing and ltching of eyes, both groups have been shown significant results.Item Efficacy of Herbal Tea as a preventive measure for Allergic Rhinitis(International Symposium on Ayurveda and Indigenous Medicine of the Ayurveda Expo 2018 – Sri Lanka organized by Ministry of Health, Nutrition & Indigenous Medicine and The National Chamber of Commerce of Sri Lanka. BMICH Colombo, Srl Lanka, 2018) Peiris, K.P.P.; Samaranayake, G.V.P.; Senadheera, M.P.R.S.Allergic rhinitis is an atopic disease. Atopic allergy is a type-I hypersensitivity reaction which produces IgE antibodies to allergens like pollen, dust, etc. In Ayurveda direct reference of allergic rhinitis is not available, but concept of allergy is scientifically ex- plained under Asatmaja Vyadhi while it's effects are explained in context of hereditary, Viruddhahara, Dushivisha and Ritu Sandhi. Various types of Pratishyaya are explained clearly in all Samhita's. However, symptoms of Vatajapratishyaya like Tanunasasrava, Shirahshoola, Kshavathu more related with symptoms of allergic rhinitis. In the present study, patients of allergic rhinitis are evaluated on the basis of general evaluation scale consisting parameters like nasal obstruction, sneezing, itching etc. In the clinical study 30 patients were selected in age between 16-60 years irrespective of their sex, religion, occupation and habitat etc. They were treated with herbal tea for 14 days in their tea time Sg of tea bag. All of them were completed the treatment accurately and the follow up study continued up to two weeks after the treatment. According to analysis, it can be concluded that, the herbal tea has been shown reducing the symptoms ofthe allergic rhinitis like nasal obstruction, sneezing, itching. Therefore for most suitable as a pre- ventive measureItem Microbiological Study of Indigenous Mouth Wash (Gandusha) for Periodontal Diseases(1st International Conference and Exhibition in Indigenous Medicine – ICEIM – 2018, Organized by Indigenous Medicine, Eastern Province with the collaboration of Unit of Siddha Medicine, Trincomalee Campus, Eastern University of Sri Lanka, 2018) Peiris, K.P.P.; Samaranayake, G.V.P.; Dewasurendra, D.M.W.Gandusha is clinically effective in the management of periodontal diseases. This study is an in-vitro analysis on determining the antimicrobial efficacy of this drug using standard Antimicrobial Sensitivity Test against a fungal culture isolated from a patient. The test was performed according to the Well diffusion method having 6mm diameter wells on Sabouraud Dextrose Agar (SDA). Each well was loaded with the test drug mixed in 20gl of sterile distilled water and fluconazole 2.5mg / ml was used as the positive control. According to the results the test drug showed an average Inhibition Zone Diameter (IZD) Of 19mm while the positive control showed IZD of 15mm. Therefore it can be stated that the test drug is more effective than the positive control 2nd the isolated culture is sensitive to the test drug as it had shown a IZD of 19mm while it is intermediate sensitive for the positive control as 15mm comes under Intermediate sensitive range (15-18mm). These results support the fact that the indigenous mouth wash (Gandusha) is effective in the management of periodontal diseasesItem Efficacy of LodradiLepa as a face cream on YuwanaPidaka(1st International Conference and Exhibition in Indigenous Medicine – ICEIM – 2018, Organized by Indigenous Medicine, Eastern Province with the collaboration of Unit of Siddha Medicine, Trincomalee Campus, Eastern University of Sri Lanka, 2018) Peiris, K.P.P.; Samaranayake, G.V.P.; Dissanayake, D.M.G.L.B.Acne is a multifactorial disease exhibiting distinct clinical presentations. Among them, the cat menial type is a matter of concern for young women. The present study aimed to evaluate the effect of overnight applications of paste made of Lotlhradi Lepa which contains Lodhra (Symplocus rasemosa), Dhanyaka (Coriandrum sativum) and Vacha (Acorus calamus). The herbal extracts used here were of the plants described in Sharangadhara Samhita. The efficacy of the treatment using the external application has been assessed through conduct oftrial in 30 patients for 3 months in a randomized. Thirty patients participated to clinical trial and completed successfully. All the patients were available to obtain measurements at all the measuring sessions. No one has complained about any c, Terience about allergy, infections or discomfort at any time that they have encountered during the follow up. Before the treatment period, 30% of patients 'were having more than 1 1 pidaka on face and after the 2 weeks treatment period patients were not having more than Il ofpidaka 53% of patients who had 6 to 10 of affected area decreased to 23 % of patients. Before the treatment period, 23% of patients were having continuous pain of lesion and after 4 weeks, 20% of patients '.vere having it. Itching and burning senation also markedly reduce after the 4 weeks of treatment. These results were proved that the face cream has worked well on reducing no ofpidaka of faceItem Management of Mukhadushika (Acne vulgaris) with Jalaukavacharana (Leech Therapy) – A Case Study(International Symposium of Ayurveda and Indigenous Medicine- Ayur Ex Kandy – 2018, Organized by the Institute of Indigenous Medicine and Provincial Department of Ayurveda, 5th – 7th October 2018, Kandy City Centre (KCC) Kandy, Sri Lanka, 2018) Samaranayake, G.V.P.; Peiris, K.P.P.; Pushpakumara, A.A.J.Jalaukavacharana (Leech Therapy) is one among the Rakfamökshana which is indicated in many kinds of skin manifestations. Similarly, Mukhadüshika (Ace vulgaris) is a common skin disease in adolescents encountered by general practitioners and dermatologists in day today clinical prac- tices. Current treatment procedures which include surgery, laser treatment, Oral antibiotics and topical applications are associated with many side effects, bacterial resistance, and irritation of the skin, peeling, scar and recurrence. But in Ayurveda, the treatment procedures like vamana, löpa, nasya and Raktamökshana are explained. Among these, Raktamök.shana using jalaukä provides a simple, painless, cost-effective treatment for Mukhadushika. A 20 years old female patient pre- sented in Shalya Clinic in Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala with the complain Of pimples on both cheeks associated with itching, burning sensation for 2 years. Patient was subjected to Jalaukävacharana on both sides Of cheeks of the face due to bilateral distribution ofpidakäs. Jalauküvacharana was done on Day I , Day 5, and Day I O. Before & after treatment assessment was recorded. Patient was followed up for 60 days.This case presented with védana, päka and shöpha, along with däha (burning sensation) and kandu (local- ized itching). Three sittings Of Jalaukävacharana were done (on Day I , Day 5, and Day 10). Here, jalaukä sucks the vitiated blood, does the sthänika shödhana. Ayurveda Raktamökshana using jalaukä provides a simple, painless, cost effective treatment for this common ailment with no short term side effectsItem Efficacy of Nutmeg as a Face Cream on Mukhadushika(International Journal of Scientific and Research Publications, 2019) Samaranayake, G.V.P.; Peiris, K.P.P.; Pushpakumara, A.A.J.Acne is a multifactorial disease exhibiting distinct clinical presentations. Among them, the cat menial type is a matter of concern for young women. The present study aimed at evaluating the effect of overnight applications of paste made of traditional herbal formulation which contains Nutmeg (Mirisfica fragrans) and Curd. The herbal extract used here were ofthe plants described in Ola leave manuscript. The efficacy of the treatment using the external application has been assessed through conduct oftrial in 30 patients for 3 months in a randomized. Thirty patients participated to clinical trial and completed successfully. All the patients were available to obtain measurements at all the masuring sessions. No one complained about any experience about allergy, infections or discomfort at any time that they have encountered during the follow up. Before the treatment period, 30% of patients were having more than I I pidaka on face and 53% of patients were having 6 to 11. 17% of patients were having up to 5 of face on yuwana pidaka in test group. After the 2 weeks treatment period patients were not having more than 11 ofpidaka 53% of patients who had 6 to I O of affected area decreased to 23% of patients. Also 37% of patients were having up to 5 of pidaka of affected area and 40% of patients were not have pidaka in test group. Patient' s results "'ere not change aner the treatment during 2 weeks Of follow up period. These results were proved that the face cream has worked well on reducing no of pidaka of face.Item The efficacy of herbal tea as a preventive measure for Allergic Rhinitis(International Journal of Multidisciplinary Research and Development, 2019) Peiris, K.P.P.; Samaranayake, G.V.P.; Senadheera, M.P.R.S.Allergic rhinitis is an atopic disease. Atcnc allergy is a type —I hypersensitivity reaction which prcxiuces lgE antibodies to allergens like pollen, dust, etc. In Ayurveda direct reference of allergic rhinitis is not available, but concept of allergy is scientifically explained under 'Asatmg_ia vyadhi' while its effects are explained in context of hereditary, Viruddhahara. Dushi visha and Ritu sandhi. Various types of Pratishyaya are explained clearly in all Samhita 's. However, symptoms of Vataja pralishyuya like Tanu nasa srava (rhinorrhel), Shirah shoola (headache), Kshavathu (sneezing) more related with symptoms Of allergic rhinitis. In the present study, patients of allergic rhinitis are evaluated cm the basis of general evaluation scale consisting parameters hike obstruction, sneezing, itching nose etc. In the clinical study 30 patients were selected in age between 16-60 years irrespective of their sex, religion, occupation and habitat etc. ney were treated with herbal tea for 14 days in their tea time 5g of tea bag. All of them were completed the treatment accurately and the follow up study contintæd up to two weeks after the treatment. According to analysis, it can be concluded that, the herbal tea has been shown reducing the symptoms of allergic rhinitis like nasal obstruction, sneezing itching. While assessing the total effect of therapy, complete remission was observed in 16.7% (n—5), marked improvement was 33.3% and moderate improvement was 50% (n: 15). During follow-up period recurrances were observed in the symptoms of running nose. Therefore it is most suitable as a preventive measure to control and cure the disease.Item A Comparative Study on the Anti-microbial efficacy of Two Ayurveda Powders (Prathisarana) Used in Periodontal Disease(International Journal of Dental Science and Innovative Research (IJDSIR), 2019) Peiris, K.P.P.; Samaranayake, G.V.P.; Wijebandara, D.M.K.KKushtadi (KU) and Karanjadi (KR) are prominently used Ayurvedic powders (Prathisarana) in the management of periodontal diseases. This study was carried out for the determination of antimicrobial efficacy of these two drugs using standard Antimicrobial Sensitivity Test against Candida albicans and a fungal culture isolated from a patient. The Antimicrobial Sensitivity Test was performed according to the Well diffusion method having 6 mm diameter wells on Sabouraud Dextrose Agar (SDA). Each well was loaded with test drugs mixed in 20 gl of sterile distilled water and fluconazole 2.5 mg/ml as the positive control. According to the results, KR showed an average Inhibition Zone Diameter (iZD) of 20 mm for the isolated culture while KU did not show any inhibition. The results were similar for Candida albicans and KR showing IZD 18 mm, KU IZD 0 mm while positive control giving an Inhibition of 25 mm. Therefore, it can be concluded that Candida albicans and the isolated culture were sensitive Only for KR making it the only effective drug out of the two drugs tested in this study.Item In-vitro Microbiological Study on; an Indigenous Mouthwash (Gandusha) for Periodontal Disease(International Journal of Recent Scientific Research, 2019) Peiris, K.P.P.; Samaranayake, G.V.P.Gandusha is clinica.lly effective in the management of perindontal disease. This study is an in-vitro anaiysis on dctcrmining the antimicrobral efficacl of the drug using standard Antimicrohial Sensitivity Test agamst a fungtrl culture isolated from a patient. Thc test was periormed according to the Well diffusion method having 6 mm diameter uells on Sahouraud Dextrose Agar (SDA). Each rr-ell rvas ioaded rrith the test drug nrired in 20 pl of sterile distilled rvater and l'luconazole 2.5 mg/ ml was used as the posrtive control. Accordrng to the results the test drug sho*'ed lnhibitory Zone Diameter (lZD) ol 1-5 mm. Therclbre rt can be stiited that the test drug is more elI'ective than the positive control and the isolated culture is sensitive to the rest drug as it had shown a IZD of l9 mm while it is intermedtate sensitive for the positive control as 15 mm comes under Intermediate Sensitive range (l-5 - 18 mm). These results support the fact that the indigenous nrouth wash (Candusha) is efttctive rn the management ofpcriodontal disease.