IPRC - 2017

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Dengue: The Cost of Illness
(In: Proceedings of the International Postgraduate Research Conference 2017 (IPRC – 2017), Faculty of Graduate Studies, University of Kelaniya, Sri Lanka., 2017) Kalansooriya, W.
Dengue is a viral infection transmitted through the bite of infected Aedes mosquitoes. It is an endemic in Sri Lanka especially in urban and suburban settings with higher transmission rates happening during the rainy season. Even though the dengue epidemic has been devastating, its consequences for the people and economy have received a little attention from economists. The economic burden of the dengue disease has many aspects. First, it affects the public budget as the government urged to allocate extra resources to treat dengue patients as well as to control the spreading of the disease. Second, it affects the individual and household budget since they have to face an unexpected expenditure for their treatments. Thirdly, getting illness reduces the number of working days of the people and therefore the overall productivity of the economy. Therefore, this study intends to identify the economic cost of dengue disease in Sri Lanka by taking a sample of 117 dengue affected people in the year 2016. The sample was selected from Maharagama division in Colombo district which is one of the high density Dengue reporting area. The selection of the sample units was on judgment base according to the prevalence data within the year. The study estimated three kinds of costs; direct medical cost, indirect cost, and other costs involved in Dengue disease. Direct medical costs include the cost associated with hospitals, doctors, nurses, use of equipment, laboratory services, prescriptions, and so on. A shadow price method was used to estimate the indirect cost which is their forgone productivity. The other costs include the extra cost bared by the patients and their families due to the illness; such as food, travelling, caring, and so on. The study found that the total cost of prevalence of dengue disease per person is approximately 74000 rupees on average while 74% of this accounts from direct medical cost, 16% from the loss of productivity and 10% from other.
Detection of Dengue Co Infections Using a Novel Single Tube Multiplex Reverse Transcription Polymerase Chain Reaction.
(In: Proceedings of the International Postgraduate Research Conference 2017 (IPRC – 2017), Faculty of Graduate Studies, University of Kelaniya, Sri Lanka., 2017) Jayathilake, E.K.S.; Jayarathne, J.A.J.C.; Muhandiramlage, T.P.; Fujii, Y.; Gunasekara, K.A.D.C.
Co-infection in individuals by more than one Dengue Virus (DENV) serotype has been reported in regions where multiple serotypes co-circulate. Co-infections can be detected using Polymerase Chain Reaction (PCR). Semi-nested multiplex PCR with Lanciotti’s primers is a widely used PCR method for serotyping DENV and it has also been used for detecting coinfections. Despite of being widely used, Lanciotti’s method may be sub-optimal in detecting co-infections as overlapping primer targets will create a bias in the amplification of the serotype with a low viral load. This could lead to underreporting of co-infections. Nine new non- overlapping primers were designed to independently amplify each serotype with minimal competition between primers to their target.In mixed infections, novel PCR assay exhibited higher sensitivity in detecting the minor serotype compared to Lanciotti’s method. The new method can also detect all four serotypes in viral RNA isolated from viral cultures and patient samples in a single tube multiplex PCR. This enables rapid and cost-effective serotyping with improved sensitivity indetection ofco-infections in clinical samples.
Optimization of Critical Threshold Values for Aedes Mosquitoes based on Breteau Index in Kandy District of Sri Lanka.
(In: Proceedings of the International Postgraduate Research Conference 2017 (IPRC – 2017), Faculty of Graduate Studies, University of Kelaniya, Sri Lanka., 2017) Udayanga, N.W.B.A.L.; Gunathilaka, P.A.D.H.N.; Iqbal, M.C.M.; Kusumawathie, P.H.D.; Abeyewickreme, W.
Many countries, including Sri Lanka, mainly depend upon Stegomyia indices,such as Premise Index (PI), Breteau Index (BI),Container Index (CI), and Pupal Index (PI) for routine entomological surveillance of dengue. Among them, BI remain as the most widely used larval index for vector management prior to and during epidemic incidences. Properly defined threshold values for BI are of essence, to assist the prediction of dengue epidemics and as a leading indicator for vector control. However, Sri Lanka still lacks effective thresholds for BI to initiate and drive dengue vector management activities. Hence, the present study attempts to define threshold values for BI based on an empirical modelling approach for the Kandy District of Sri Lanka.
Knowledge and Practices towards Prevention of Dengue Fever in a Cohort of Advanced Level Students.
(In: Proceedings of the International Postgraduate Research Conference 2017 (IPRC – 2017), Faculty of Graduate Studies, University of Kelaniya, Sri Lanka., 2017) Mathangasinghe, Y.; Jayasooriya, U.G.L.B.
The objective of this study was to assess the knowledge and practices towards Dengue fever (DF) of a group of Sri Lankan students. Materials and methods: This was a combined qualitative and quantitative study from June to July 2016. Students in the Advanced Level classes of a trilingual mixed school following different streams (Science, Mathematics, Arts, and Commerce) were enrolled using the cluster sampling method. A face-validated self-administered questionnaire and in-depth interviews were used to collect data.

IPRC - 2017

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