Medicine

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This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty

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Author: search.filters.author.Bundy, D.A.P.Subject: search.filters.subject.Helminthiasis

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    Intestinal Nematodes: Ascariasis
    (Elsevier, 2020) Bundy, D.A.P.; de Silva, N.R.; Appleby, L.J.; Brooker, S.J.
    Ascariasis is the most prevalent human helminth infection, with an estimated 819 million infections worldwide. Transmission primarily occurs in warm, tropical climates that lack water and sanitation facilities and have poor hygiene. Worms inhabit the small intestine, and morbidity is related to worm burden. A small proportion of the infected population harbors the majority of worms, with intense infection most common in school-age children, and intensity and prevalence declining to a low level throughout adulthood. School-age children are therefore the targets for school-based community control efforts in large-scale treatment campaigns. Light infections can affect growth and development, whereas, due to the size of the worms, heavier worm burdens can result in intestinal obstruction, particularly in young children. Treatment with mebendazole or albendazole is efficacious, with cure rates of >90% commonly achieved.
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    Intestinal nematodes that migrate through lungs (Ascariasis)
    (WB Saunders Company, 2000) de Silva, N.R.; Bundy, D.A.P.
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    Can we deworm this wormy world?
    (Oxford University Press, 1998) Bundy, D.A.P.; de Silva, N.R.
    While programmes such as the Rockefeller campaign were specifically targeted at a particular parasite species, the current trend is towards the simultaneous control of all the major geohelminth species. New, broad-spectrum, low-cost anthelmintics and new understanding of epidemiology have led to more cost-effective and sustainable strategies. The WHO, UNICEF and the World Bank all now support global and regional efforts to achieve control of morbidity from intestinal worms. In this paper, we aim to show what's new in clinical helminthology and what has brought about the great improvement in the success of the new approaches to control.
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